Antibodies to the inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) in cerebellar ataxia

We report on a serum autoantibody associated with cerebellar ataxia. Immunohistochemical studies of sera from four patients referred for autoantibody testing revealed binding of high-titer (up to 1:5,000) IgG antibodies, mainly IgG1, to the molecular layer, Purkinje cell layer, and white matter on m...

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Publicat a:J Neuroinflammation
Autors principals: Jarius, Sven, Scharf, Madeleine, Begemann, Nora, Stöcker, Winfried, Probst, Christian, Serysheva, Irina I, Nagel, Sigrun, Graus, Francesc, Psimaras, Dimitri, Wildemann, Brigitte, Komorowski, Lars
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300617/
https://ncbi.nlm.nih.gov/pubmed/25498830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-014-0206-3
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