Inositol 1,4,5-trisphosphate receptor type 1 autoantibodies in paraneoplastic and non-paraneoplastic peripheral neuropathy

BACKGROUND: Recently, we described a novel autoantibody, anti-Sj/ITPR1-IgG, that targets the inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) in patients with cerebellar ataxia. However, ITPR1 is expressed not only by Purkinje cells but also in the anterior horn of the spinal cord, in the substa...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Jarius, Sven, Ringelstein, Marius, Haas, Jürgen, Serysheva, Irina I., Komorowski, Lars, Fechner, Kai, Wandinger, Klaus-Peter, Albrecht, Philipp, Hefter, Harald, Moser, Andreas, Neuen-Jacob, Eva, Hartung, Hans-Peter, Wildemann, Brigitte, Aktas, Orhan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5078930/
https://ncbi.nlm.nih.gov/pubmed/27776522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0737-x
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