Closing the cohesin ring: structure and function of its Smc3-kleisin interface

Through their association with a kleisin subunit (Scc1), cohesin’s Smc1 and Smc3 subunits are thought to form tripartite rings that mediate sister chromatid cohesion. Unlike the structure of Smc1/Smc3 and Smc1/Scc1 interfaces, that of Smc3/Scc1 is not known. Disconnection of this interface is though...

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Bibliographic Details
Published in:Science
Main Authors: Gligoris, Thomas G., Scheinost, Johanna C., Bürmann, Frank, Petela, Naomi, Chan, Kok-Lung, Uluocak, Pelin, Beckouët, Frédéric, Gruber, Stephan, Nasmyth, Kim, Löwe, Jan
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300515/
https://ncbi.nlm.nih.gov/pubmed/25414305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1256917
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