Thrombin induces ischemic LTP (iLTP): implications for synaptic plasticity in the acute phase of ischemic stroke

Acute brain ischemia modifies synaptic plasticity by inducing ischemic long-term potentiation (iLTP) of synaptic transmission through the activation of N-Methyl-D-aspartate receptors (NMDAR). Thrombin, a blood coagulation factor, affects synaptic plasticity in an NMDAR dependent manner. Since its ac...

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Publicado no:Sci Rep
Main Authors: Stein, Efrat Shavit, Itsekson-Hayosh, Zeev, Aronovich, Anna, Reisner, Yair, Bushi, Doron, Pick, Chaim G., Tanne, David, Chapman, Joab, Vlachos, Andreas, Maggio, Nicola
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300504/
https://ncbi.nlm.nih.gov/pubmed/25604482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07912
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