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Annotation of genomics data using bidirectional hidden Markov models unveils variations in Pol II transcription cycle

DNA replication, transcription and repair involve the recruitment of protein complexes that change their composition as they progress along the genome in a directed or strand-specific manner. Chromatin immunoprecipitation in conjunction with hidden Markov models (HMMs) has been instrumental in under...

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Detalhes bibliográficos
Publicado no:Mol Syst Biol
Main Authors: Zacher, Benedikt, Lidschreiber, Michael, Cramer, Patrick, Gagneur, Julien, Tresch, Achim
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300491/
https://ncbi.nlm.nih.gov/pubmed/25527639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20145654
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