Emerging Role of Linker Histone Variant H1x as a Biomarker with Prognostic Value in Astrocytic Gliomas. A Multivariate Analysis including Trimethylation of H3K9 and H4K20

Although epigenetic alterations play an essential role in gliomagenesis, the relevance of aberrant histone modifications and the respective enzymes has not been clarified. Experimental data implicates histone H3 lysine (K) methyltransferases SETDB1 and SUV39H1 into glioma pathobiology, whereas linke...

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Pubblicato in:PLoS One
Autori principali: Sepsa, Athanasia, Levidou, Georgia, Gargalionis, Antonis, Adamopoulos, Christos, Spyropoulou, Anastasia, Dalagiorgou, Georgia, Thymara, Irene, Boviatsis, Efstathios, Themistocleous, Marios S., Petraki, Kalliopi, Vrettakos, George, Samaras, Vassilis, Zisakis, Athanassios, Patsouris, Efstratios, Piperi, Christina, Korkolopoulou, Penelope
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300227/
https://ncbi.nlm.nih.gov/pubmed/25602259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115101
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