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Pharmacokinetics of Cefaclor in Normal Subjects and Patients with Chronic Renal Failure

We studied the pharmacokinetics of cefaclor, a new cephalosporin antibiotic, in normal subjects and subjects with chronic renal failure. Cefaclor was largely, but not entirely, eliminated by the kidneys. The cefaclor half-life in normal subjects was 40 to 60 min; in subjects with essentially no rena...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Bloch, Richard, Szwed, James J., Sloan, Rebecca S., Luft, Friedrich C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1977
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC430012/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/931372/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.12.6.730
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