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Pharmacology of a New 1-Oxa-β-lactam (LY127935) in Normal Volunteers

The pharmacokinetics of 1-oxa-β-lactam (LY127935), a new semisynthetic β-lactam antibiotic, was studied in four healthy adult volunteers (mean age of 27 years, mean body surface area ± standard error [SE] of 1.87 ± 0.08 m(2), and mean creatinine clearance ± SE of 116 ± 12 ml/min per 1.73 m(2)). Imme...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Parsons, James N., Romano, Joseph M., Levison, Matthew E.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1980
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283762/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6446259/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.17.2.226
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