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GENOME-WIDE GENETIC INTERACTION ANALYSIS OF GLAUCOMA USING EXPERT KNOWLEDGE DERIVED FROM HUMAN PHENOTYPE NETWORKS

The large volume of GWAS data poses great computational challenges for analyzing genetic interactions associated with common human diseases. We propose a computational framework for characterizing epistatic interactions among large sets of genetic attributes in GWAS data. We build the human phenotyp...

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Bibliografiske detaljer
Udgivet i:Pac Symp Biocomput
Main Authors: HU, TING, DARABOS, CHRISTIAN, CRICCO, MARIA E., KONG, EMILY, MOORE, JASON H.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299930/
https://ncbi.nlm.nih.gov/pubmed/25592582
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