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GENOME-WIDE GENETIC INTERACTION ANALYSIS OF GLAUCOMA USING EXPERT KNOWLEDGE DERIVED FROM HUMAN PHENOTYPE NETWORKS

The large volume of GWAS data poses great computational challenges for analyzing genetic interactions associated with common human diseases. We propose a computational framework for characterizing epistatic interactions among large sets of genetic attributes in GWAS data. We build the human phenotyp...

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Detalhes bibliográficos
Publicado no:Pac Symp Biocomput
Main Authors: HU, TING, DARABOS, CHRISTIAN, CRICCO, MARIA E., KONG, EMILY, MOORE, JASON H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299930/
https://ncbi.nlm.nih.gov/pubmed/25592582
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