Autologous Transfusion of Stored Red Blood Cells Increases Pulmonary Artery Pressure

Rationale: Transfusion of erythrocytes stored for prolonged periods is associated with increased mortality. Erythrocytes undergo hemolysis during storage and after transfusion. Plasma hemoglobin scavenges endogenous nitric oxide leading to systemic and pulmonary vasoconstriction. Objectives: We hypo...

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Detalhes bibliográficos
Publicado no:Am J Respir Crit Care Med
Main Authors: Berra, Lorenzo, Pinciroli, Riccardo, Stowell, Christopher P., Wang, Lin, Yu, Binglan, Fernandez, Bernadette O., Feelisch, Martin, Mietto, Cristina, Hod, Eldad A., Chipman, Daniel, Scherrer-Crosbie, Marielle, Bloch, Kenneth D., Zapol, Warren M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299609/
https://ncbi.nlm.nih.gov/pubmed/25162920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201405-0850OC
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