Autologous Transfusion of Stored Red Blood Cells Increases Pulmonary Artery Pressure

Rationale: Transfusion of erythrocytes stored for prolonged periods is associated with increased mortality. Erythrocytes undergo hemolysis during storage and after transfusion. Plasma hemoglobin scavenges endogenous nitric oxide leading to systemic and pulmonary vasoconstriction. Objectives: We hypo...

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Bibliografske podrobnosti
izdano v:Am J Respir Crit Care Med
Main Authors: Berra, Lorenzo, Pinciroli, Riccardo, Stowell, Christopher P., Wang, Lin, Yu, Binglan, Fernandez, Bernadette O., Feelisch, Martin, Mietto, Cristina, Hod, Eldad A., Chipman, Daniel, Scherrer-Crosbie, Marielle, Bloch, Kenneth D., Zapol, Warren M.
Format: Artigo
Jezik:Inglês
Izdano: American Thoracic Society 2014
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299609/
https://ncbi.nlm.nih.gov/pubmed/25162920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201405-0850OC
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