Pulmonary Hypertension in Lambs Transfused with Stored Blood is Prevented by Breathing Nitric Oxide

BACKGROUND: During extended storage, erythrocytes undergo functional changes. These changes reduce the viability of erythrocytes leading to release of oxyhemoglobin, a potent scavenger of nitric oxide. We hypothesized that transfusion of ovine packed erythrocytes (PRBC) stored for prolonged periods...

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Detalhes bibliográficos
Main Authors: Baron, David M., Yu, Binglan, Lei, Chong, Bagchi, Aranya, Beloiartsev, Arkadi, Stowell, Christopher P., Steinbicker, Andrea U., Malhotra, Rajeev, Bloch, Kenneth D., Zapol, Warren M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293704/
https://ncbi.nlm.nih.gov/pubmed/22293717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e318246ef77
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