Adverse Effects of Hemorrhagic Shock Resuscitation with Stored Blood are Ameliorated by Inhaled Nitric Oxide in Lambs

OBJECTIVES: Transfusion of stored red blood cells (RBCs) is associated with increased morbidity and mortality in trauma patients. Plasma hemoglobin scavenges nitric oxide (NO), which can cause vasoconstriction, induce inflammation and activate platelets. We hypothesized that transfusion of RBCs stor...

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Detalhes bibliográficos
Main Authors: Baron, David M., Beloiartsev, Arkadi, Nakagawa, Akito, Martyn, Trejeeve, Stowell, Christopher P., Malhotra, Rajeev, Mayeur, Claire, Bloch, Kenneth D., Zapol, Warren M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812272/
https://ncbi.nlm.nih.gov/pubmed/23887236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0b013e31828cf456
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