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Multi-input CRISPR/Cas genetic circuits that interface host regulatory networks
Genetic circuits require many regulatory parts in order to implement signal processing or execute algorithms in cells. A potentially scalable approach is to use dCas9, which employs small guide RNAs (sgRNAs) to repress genetic loci via the programmability of RNA:DNA base pairing. To this end, we use...
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| Publicat a: | Mol Syst Biol |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Blackwell Publishing Ltd
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4299604/ https://ncbi.nlm.nih.gov/pubmed/25422271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20145735 |
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