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Protein surface charge of trypsinogen changes its activation pattern

BACKGROUND: Trypsinogen is the inactive precursor of trypsin, a serine protease that cleaves proteins and peptides after arginine and lysine residues. In this study, human trypsinogen was used as a model protein to study the influence of electrostatic forces on protein–protein interactions. Trypsino...

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Publicat a:BMC Biotechnol
Autors principals: Buettner, Karin, Kreisig, Thomas, Sträter, Norbert, Zuchner, Thole
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299543/
https://ncbi.nlm.nih.gov/pubmed/25543846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-014-0109-5
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