Neuroblastoma patient-derived orthotopic xenografts retain metastatic patterns and geno- and phenotypes of patient tumours

Neuroblastoma is a childhood tumour with heterogeneous characteristics and children with metastatic disease often have a poor outcome. Here we describe the establishment of neuroblastoma patient-derived xenografts (PDXs) by orthotopic implantation of viably cryopreserved or fresh tumour explants of...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: Braekeveldt, Noémie, Wigerup, Caroline, Gisselsson, David, Mohlin, Sofie, Merselius, My, Beckman, Siv, Jonson, Tord, Börjesson, Anna, Backman, Torbjörn, Tadeo, Irene, Berbegall, Ana P, Öra, Ingrid, Navarro, Samuel, Noguera, Rosa, Påhlman, Sven, Bexell, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Periodicals, Inc 2015
Assuntos:
Cancer Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299502/
https://ncbi.nlm.nih.gov/pubmed/25220031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.29217
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