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The Good, the Bad, and the Ugly: in search of gold standards for assessing functional genetic screen quality
Variable screen quality, off-target effects, and unclear false discovery rates often hamper large-scale functional genomic screens in mammalian cells. Hart et al (2014) introduce gold standard reference sets of essential and non-essential genes, aiming at standardizing the analysis of genome-wide sc...
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| Pubblicato in: | Mol Syst Biol |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Blackwell Publishing Ltd
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4299495/ https://ncbi.nlm.nih.gov/pubmed/24987117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20145372 |
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