Epstein–Barr virus nuclear antigen 3A partially coincides with EBNA3C genome-wide and is tethered to DNA through BATF complexes

Epstein–Barr Virus (EBV) conversion of B-lymphocytes to Lymphoblastoid Cell Lines (LCLs) requires four EBV nuclear antigen (EBNA) oncoproteins: EBNA2, EBNALP, EBNA3A, and EBNA3C. EBNA2 and EBNALP associate with EBV and cell enhancers, up-regulate the EBNA promoter, MYC, and EBV Latent infection Memb...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Schmidt, Stefanie C. S., Jiang, Sizun, Zhou, Hufeng, Willox, Bradford, Holthaus, Amy M., Kharchenko, Peter V., Johannsen, Eric C., Kieff, Elliott, Zhao, Bo
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2015
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299249/
https://ncbi.nlm.nih.gov/pubmed/25540416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1422580112
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