Immunological consequences of intragenus conservation of Mycobacterium tuberculosis T-cell epitopes

A previous unbiased genome-wide analysis of CD4 Mycobacterium tuberculosis (MTB) recognition using peripheral blood mononuclear cells from individuals with latent MTB infection (LTBI) or nonexposed healthy controls (HCs) revealed that certain MTB sequences were unexpectedly recognized by HCs. In the...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Lindestam Arlehamn, Cecilia S., Paul, Sinu, Mele, Federico, Huang, Charlie, Greenbaum, Jason A., Vita, Randi, Sidney, John, Peters, Bjoern, Sallusto, Federica, Sette, Alessandro
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2015
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299226/
https://ncbi.nlm.nih.gov/pubmed/25548174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1416537112
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