In Vivo Microdialysis Reveals Age-Dependent Decrease of Brain Interstitial Fluid Tau Levels in P301S Human Tau Transgenic Mice

Although tau is a cytoplasmic protein, it is also found in brain extracellular fluids, e.g., CSF. Recent findings suggest that aggregated tau can be transferred between cells and extracellular tau aggregates might mediate spread of tau pathology. Despite these data, details of whether tau is normall...

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Publicado no:J Neurosci
Main Authors: Yamada, Kaoru, Cirrito, John R., Stewart, Floy R., Jiang, Hong, Finn, Mary Beth, Holmes, Brandon B., Binder, Lester I., Mandelkow, Eva-Maria, Diamond, Marc I., Lee, Virginia M.-Y., Holtzman, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299126/
https://ncbi.nlm.nih.gov/pubmed/21917794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2569-11.2011
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