Antiviral Activity of Arabinosylthymine in Herpesviral Replication: Mechanism of Action In Vivo and In Vitro

1-β-d-Arabinofuranosylthymine (ara-T), a metabolite of the sponge Tethya crypta, has shown selective activity against herpes simplex virus (HSV) replication (G. A. Gentry and J. F. Aswell, Virology 65:294–296, 1975). Analysis of HSV-infected and uninfected cell lysates by CsCl isopycnic centrifugati...

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Bibliographic Details

Published in:	Antimicrob Agents Chemother
Main Authors:	Aswell, J. F., Allen, G. P., Jamieson, A. T., Campbell, D. E., Gentry, G. A.
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 1977
Subjects:	Biosynthesis; Chemistry; Mechanisms of Action and Resistance
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429893/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/197886/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.12.2.243
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