Antiviral Activity of Arabinosylthymine in Herpesviral Replication: Mechanism of Action In Vivo and In Vitro

1-β-d-Arabinofuranosylthymine (ara-T), a metabolite of the sponge Tethya crypta, has shown selective activity against herpes simplex virus (HSV) replication (G. A. Gentry and J. F. Aswell, Virology 65:294–296, 1975). Analysis of HSV-infected and uninfected cell lysates by CsCl isopycnic centrifugati...

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Main Authors: Aswell, J. F., Allen, G. P., Jamieson, A. T., Campbell, D. E., Gentry, G. A.
Format: Artigo
Sprog:Inglês
Udgivet: 1977
Fag:
Biosynthesis; Chemistry; Mechanisms of Action and Resistance
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC429893/
https://ncbi.nlm.nih.gov/pubmed/197886
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