Arrest of Myelination and Reduced Axon Growth When Schwann Cells Lack mTOR

In developing peripheral nerves, differentiating Schwann cells sort individual axons from bundles and ensheath them to generate multiple layers of myelin. In recent years, there has been an increased understanding of the extracellular and intracellular factors that initiate and stimulate Schwann cel...

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Vydáno v:J Neurosci
Hlavní autoři: Sherman, Diane L., Krols, Michiel, Wu, Lai-Man N., Grove, Matthew, Nave, Klaus-Armin, Gangloff, Yann-Gaël, Brophy, Peter J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298696/
https://ncbi.nlm.nih.gov/pubmed/22302821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4814-11.2012
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