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The Nck-interacting kinase NIK increases Arp2/3 complex activity by phosphorylating the Arp2 subunit
The nucleating activity of the Arp2/3 complex promotes the assembly of branched actin filaments that drive plasma membrane protrusion in migrating cells. Arp2/3 complex binding to nucleation-promoting factors of the WASP and WAVE families was previously thought to be sufficient to increase nucleatin...
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| Publicado en: | J Cell Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Rockefeller University Press
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4298681/ https://ncbi.nlm.nih.gov/pubmed/25601402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201404095 |
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