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Carbon monoxide down-modulates Toll-like receptor 4/MD2 expression on innate immune cells and reduces endotoxic shock susceptibility

Carbon monoxide (CO) has been recently reported as the main anti-inflammatory mediator of the haem-degrading enzyme haem-oxygenase 1 (HO-1). It has been shown that either HO-1 induction or CO treatment reduces the ability of monocytes to respond to inflammatory stimuli, such as lipopolysaccharide (L...

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Bibliographic Details
Published in:Immunology
Main Authors: Riquelme, Sebastián A, Bueno, Susan M, Kalergis, Alexis M
Format: Artigo
Language:Inglês
Published: BlackWell Publishing Ltd 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298426/
https://ncbi.nlm.nih.gov/pubmed/25179131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12375
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