Serum amyloid A induces interleukin-1β secretion from keratinocytes via the NACHT, LRR and PYD domains-containing protein 3 inflammasome

Interleukin (IL)-1β is now emerging as a critical cytokine in the pathogenesis of T helper type 17 (Th17)-mediated skin diseases, including psoriasis. Psoriatic keratinocytes are a major source of IL-1β; however, the mechanisms triggering IL-1β processing remain unknown. Recently, an acute-phase pro...

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Bibliografiska uppgifter
I publikationen:Clin Exp Immunol
Huvudupphovsmän: Yu, N, Liu, S, Yi, X, Zhang, S, Ding, Y
Materialtyp: Artigo
Språk:Inglês
Publicerad: BlackWell Publishing Ltd 2015
Ämnen:
Original Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298410/
https://ncbi.nlm.nih.gov/pubmed/25231464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12458
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