Zinc transporter 8 (ZnT8) autoantibody epitope specificity and affinity examined with recombinant ZnT8 variant proteins in specific ZnT8R and ZnT8W autoantibody-positive type 1 diabetes patients

Variant-specific zinc transporter 8 autoantibodies (ZnT8A) against either arginine (R) or tryptophan (W) at amino acid (aa) position 325 of the zinc transporter 8 (ZnT8) has been identified in type 1 diabetes (T1D) patients. Reciprocal cross-over tests revealed differences in half-maximal binding to...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Clin Exp Immunol
Prif Awduron: Skärstrand, H, Krupinska, E, Haataja, T J K, Vaziri-Sani, F, Lagerstedt, J O, Lernmark, Å
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BlackWell Publishing Ltd 2015
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298399/
https://ncbi.nlm.nih.gov/pubmed/25178386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12448
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg