Aged iPSCs display an uncommon mitochondrial appearance and fail to undergo in vitro neurogenesis

Reprogramming of human fibroblasts into induced pluripotent stem cells (iPSCs) leads to mitochondrial rejuvenation, making iPSCs a candidate model to study the mitochondrial biology during stemness and differentiation. At present, it is generally accepted that iPSCs can be maintained and propagated...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Aging (Albany NY)
Prif Awduron: Masotti, Andrea, Celluzzi, Antonella, Petrini, Stefania, Bertini, Enrico, Zanni, Ginevra, Compagnucci, Claudia
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2014
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298368/
https://ncbi.nlm.nih.gov/pubmed/25567319
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