Characterizing PCDH19 in human induced pluripotent stem cells (iPSCs) and iPSC-derived developing neurons: emerging role of a protein involved in controlling polarity during neurogenesis

PCDH19 (Protocadherin 19), a member of the cadherin superfamily, is involved in the pathogenic mechanism of an X-linked model of neurological disease. The biological function of PCHD19 in human neurons and during neurogenesis is currently unknown. Therefore, we decided to use the model of the induce...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Compagnucci, Claudia, Petrini, Stefania, Higuraschi, Norimichi, Trivisano, Marina, Specchio, Nicola, Hirose, Shinichi, Bertini, Enrico, Terracciano, Alessandra
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper: Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694954/
https://ncbi.nlm.nih.gov/pubmed/26450854
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