Characterization of the host–guest complex of a curcumin analog with β-cyclodextrin and β-cyclodextrin–gemini surfactant and evaluation of its anticancer activity

BACKGROUND: Curcumin analogs, including the novel compound NC 2067, are potent cytotoxic agents that suffer from poor solubility, and hence, low bioavailability. Cyclodextrin-based carriers can be used to encapsulate such agents. In order to understand the interaction between the two molecules, the...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Poorghorban, Masoomeh, Das, Umashankar, Alaidi, Osama, Chitanda, Jackson M, Michel, Deborah, Dimmock, Jonathan, Verrall, Ronald, Grochulski, Pawel, Badea, Ildiko
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298337/
https://ncbi.nlm.nih.gov/pubmed/25609956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S70828
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