Peroxiredoxin-2 Recycling Is Inhibited During Erythrocyte Storage

Aims: Transfusion with stored red blood cells (RBCs) is associated with increased morbidity and mortality. Peroxiredoxin-2 (Prx-2) is a primary RBC antioxidant that limits hydrogen peroxide (H(2)O(2))-mediated toxicity. Whether Prx-2 activity is altered during RBC storage is not known. Results: Basa...

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Bibliographische Detailangaben
Veröffentlicht in:Antioxid Redox Signal
Hauptverfasser: Harper, Victoria M., Oh, Joo Yeun, Stapley, Ryan, Marques, Marisa B., Wilson, Landon, Barnes, Stephen, Sun, Chiao-Wang, Townes, Tim, Patel, Rakesh P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2015
Schlagworte:
Original Research Communications
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298151/
https://ncbi.nlm.nih.gov/pubmed/25264713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2014.5950
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