Oxymetholone Therapy of Fanconi Anemia Suppresses Osteopontin Transcription and Induces Hematopoietic Stem Cell Cycling

Androgens are widely used for treating Fanconi anemia (FA) and other human bone marrow failure syndromes, but their mode of action remains incompletely understood. Aged Fancd2(−/−) mice were used to assess the therapeutic efficacy of oxymetholone (OXM) and its mechanism of action. Eighteen-month-old...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Stem Cell Reports
Asıl Yazarlar: Zhang, Qing-Shuo, Benedetti, Eric, Deater, Matthew, Schubert, Kathryn, Major, Angela, Pelz, Carl, Impey, Soren, Marquez-Loza, Laura, Rathbun, R. Keaney, Kato, Shigeaki, Bagby, Grover C., Grompe, Markus
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297866/
https://ncbi.nlm.nih.gov/pubmed/25434823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.10.014
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller