Krüppel-like factor 4 is a radioprotective factor for the intestine following γ-radiation-induced gut injury in mice

Gut radiation-induced injury is a concern during treatment of patients with cancer. Krüppel-like factor 4 (KLF4) is expressed in differentiated villous epithelial cells of the small intestine. We previously showed that KLF4 protects cells from apoptosis following γ-irradiation in vitro. We sought to...

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Detalles Bibliográficos
Publicado en:Am J Physiol Gastrointest Liver Physiol
Autores principales: Talmasov, Daniel, Zhang, Xinjun, Yu, Bing, Nandan, Mandayam O., Bialkowska, Agnieszka B., Elkarim, Enas, Kuruvilla, Jes, Yang, Vincent W., Ghaleb, Amr M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2014
Materias:
Mucosal Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297857/
https://ncbi.nlm.nih.gov/pubmed/25414097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00080.2014
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