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The role of slow and persistent TTX-resistant sodium currents in acute tumor necrosis factor-α-mediated increase in nociceptors excitability

Tetrodotoxin-resistant (TTX-r) sodium channels are key players in determining the input-output properties of peripheral nociceptive neurons. Changes in gating kinetics or in expression levels of these channels by proinflammatory mediators are likely to cause the hyperexcitability of nociceptive neur...

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Detalhes bibliográficos
Publicado no:J Neurophysiol
Main Authors: Gudes, Sagi, Barkai, Omer, Caspi, Yaki, Katz, Ben, Lev, Shaya, Binshtok, Alexander M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297796/
https://ncbi.nlm.nih.gov/pubmed/25355965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00652.2014
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