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TTX-Resistant Sodium Channels Functionally Separate Silent From Polymodal C-nociceptors

Pronounced activity-dependent slowing of conduction has been used to characterize mechano-insensitive, “silent” nociceptors and might be due to high expression of Na(V)1.8 and could, therefore, be characterized by their tetrodotoxin-resistance (TTX-r). Nociceptor-class specific differences in action...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Jonas, Robin, Prato, Vincenzo, Lechner, Stefan G., Groen, Gerbrand, Obreja, Otilia, Werland, Fiona, Rukwied, Roman, Klusch, Andreas, Petersen, Marlen, Carr, Richard W., Schmelz, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7018684/
https://ncbi.nlm.nih.gov/pubmed/32116559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.00013
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