Organ-Specific Protective Role of NKT Cells in Virus-Induced Inflammatory Demyelination and Myocarditis Depends on Mouse Strain

Theiler’s murine encephalomyelitis virus (TMEV) can induce demyelination or myocarditis in susceptible mouse strains. A deficiency of NKT cells exacerbated TMEV-induced demyelinating disease (TMEV-IDD) in SJL/J and BALB/c mice. In C57BL/6 background, however, NKT-cell-deficient Jαt 18 KO mice remain...

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Udgivet i:J Neuroimmunol
Main Authors: Kawai, Eiichiro, Sato, Fumitaka, Omura, Seiichi, Martinez, Nicholas E., Reddy, Pratap C., Taniguchi, Masaru, Tsunoda, Ikuo
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297752/
https://ncbi.nlm.nih.gov/pubmed/25434008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2014.11.003
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