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Both rejection and tolerance of allografts can occur in the absence of secondary lymphoid tissues
In this study, we show that aly/aly mice, which are devoid of lymph nodes and Peyer’s patches, rejected acutely fully allogeneic skin and heart grafts. They mounted potent inflammatory direct alloresponses but failed to develop indirect alloreactivity after transplantation. Remarkably, skin allograf...
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| 出版年: | J Immunol |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4297718/ https://ncbi.nlm.nih.gov/pubmed/25535285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401157 |
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