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Both rejection and tolerance of allografts can occur in the absence of secondary lymphoid tissues
In this study, we show that aly/aly mice, which are devoid of lymph nodes and Peyer’s patches, rejected acutely fully allogeneic skin and heart grafts. They mounted potent inflammatory direct alloresponses but failed to develop indirect alloreactivity after transplantation. Remarkably, skin allograf...
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| Publicado no: | J Immunol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4297718/ https://ncbi.nlm.nih.gov/pubmed/25535285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401157 |
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