Annexin 2-CXCL12 Interactions Regulate Metastatic Cell Targeting and Growth in the Bone Marrow

A nnexin 2 (ANXA2) plays a critical role in hematopoietic stem cell (HSC) localization to the marrow niche. In part, ANXA2 supports HSCs by serving as an anchor for stromal-derived factor-1 (CXCL12/SDF-1). Recently it was demonstrated that prostate cancer (PCa) cells, like HSCs, use ANXA2 to establi...

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Bibliografske podrobnosti
izdano v:Mol Cancer Res
Main Authors: Jung, Younghun, Wang, Jingcheng, Lee, Eunsohl, McGee, Samantha, Berry, Janice E., Yumoto, Kenji, Dai, Jinlu, Keller, Evan T., Shiozawa, Yusuke, Taichman, Russell S.
Format: Artigo
Jezik:Inglês
Izdano: 2014
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297714/
https://ncbi.nlm.nih.gov/pubmed/25139998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-14-0118
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