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Concentrations of Trimethoprim-Sulfamethoxazole in Blood After a Single, Large Oral Dose

Concentrations of trimethoprim (TMP) and sulfamethoxazole (SMZ) in blood were determined in seven healthy volunteers after ingestion of 720 mg of TMP and 3,600 mg of SMZ (nine tablets of TMP-SMZ, 1:5 ratio) as a single oral dose. The mean levels of drug in blood achieved during the first 8 h after d...

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Bibliografische gegevens
Gepubliceerd in:Antimicrob Agents Chemother
Hoofdauteurs: Yoshikawa, Thomas T., Guze, Lucien B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 1976
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429771/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/984788/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.10.3.462
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