MMP-9 expression is increased in B lymphocytes during multiple sclerosis exacerbation and is regulated by microRNA-320a

B cells are necessary to maintain disease activity in relapsing multiple sclerosis (MS) and produce matrix metallopeptidase-9 (MMP-9), which disrupts the blood-brain barrier. MMP-9 protein expression was increased and expression of microRNA-320a (miR-320a), which targets MMP-9 mRNA, was significantl...

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Vydáno v:J Neuroimmunol
Hlavní autoři: Aung, Latt L., Mouradian, M. Maral, Dhib-Jalbut, Suhayl, Balashov, Konstantin E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297694/
https://ncbi.nlm.nih.gov/pubmed/25468268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2014.11.004
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