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Enhancement of stress resilience through Hdac6-mediated regulation of glucocorticoid receptor chaperone dynamics
BACKGROUND: Acetylation of Hsp90 regulates downstream hormone signaling via the glucocorticoid receptor (GR), but the role of this molecular mechanism in stress homeostasis remains poorly understood. We tested whether acetylation of Hsp90 in the brain predicts and modulates the behavioral sequelae o...
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| Publié dans: | Biol Psychiatry |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4297530/ https://ncbi.nlm.nih.gov/pubmed/25442004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2014.07.036 |
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