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Dynamic expression of T-bet and GATA3 by regulatory T cells maintains immune tolerance

Regulatory T (T(reg)) cells can express the transcription factors T-bet and GATA3 but the function of this expression and whether such cells represent stable subsets is still unknown. By using multiple reporter tools, we show that the expression of T-bet and GATA3 in T(reg) cells is dynamically infl...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Immunol
Prif Awduron: Yu, Fang, Sharma, Suveena, Edwards, Julie, Feigenbaum, Lionel, Zhu, Jinfang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297509/
https://ncbi.nlm.nih.gov/pubmed/25501630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3053
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