TDP-43 pathology in the basal forebrain and hypothalamus of patients with amyotrophic lateral sclerosis

INTRODUCTION: Amyotrophic lateral sclerosis is a neurodegenerative disease characterized clinically by motor symptoms including limb weakness, dysarthria, dysphagia, and respiratory compromise, and pathologically by inclusions of transactive response DNA-binding protein 43 kDa (TDP-43). Patients wit...

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Bibliographic Details
Published in:Acta Neuropathol Commun
Main Authors: Cykowski, Matthew D, Takei, Hidehiro, Schulz, Paul E, Appel, Stanley H, Powell, Suzanne Z
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297460/
https://ncbi.nlm.nih.gov/pubmed/25539830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-014-0171-1
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