A droplet digital PCR detection method for rare L1 insertions in tumors

BACKGROUND: The active human mobile element, long interspersed element 1 (L1) currently populates human genomes in excess of 500,000 copies per haploid genome. Through its mobility via a process called target primed reverse transcription (TPRT), L1 mobilization has resulted in over 100 de novo cases...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mob DNA
Auteurs principaux: White, Travis B, McCoy, Adam M, Streva, Vincent A, Fenrich, Joshua, Deininger, Prescott L
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297411/
https://ncbi.nlm.nih.gov/pubmed/25598847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13100-014-0030-4
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