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Comparative Pharmacokinetics and Metabolism of Cephapirin in Laboratory Animals and Humans

Comparative drug disposition studies in mice, rats, dogs, and humans indicate that cephapirin, a new semisynthetic cephalosporin antibiotic that exhibits broad-spectrum antimicrobial activity, is metabolized to desacetylcephapirin in these species. Pharmacokinetic analyses of the concentrations of c...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Cabana, B. E., Harken, D. R. Van, Hottendorf, G. H.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1976
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429740/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/984774/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.10.2.307
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