Comparative Pharmacokinetics and Metabolism of Cephapirin in Laboratory Animals and Humans

Comparative drug disposition studies in mice, rats, dogs, and humans indicate that cephapirin, a new semisynthetic cephalosporin antibiotic that exhibits broad-spectrum antimicrobial activity, is metabolized to desacetylcephapirin in these species. Pharmacokinetic analyses of the concentrations of c...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Cabana, B. E., Harken, D. R. Van, Hottendorf, G. H.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1976
Soggetti:	Pharmacology and Therapeutics
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429740/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/984774/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.10.2.307
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