Pharmacokinetics of chewed vs. swallowed raltegravir in a patient with AIDS and MAI infection: some new conflicting data

BACKGROUND: While HIV, AIDS and atypical Mycobacterium infections are closely linked, the use of Integrase-Inhibitor based cART, notably raltegravir-based regimens is more widespread. RAL should be double-dosed to 800 mg semi-daily in situation of rifampicin co-medication, because RAL is more rapidl...

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Bibliographic Details
Published in:AIDS Res Ther
Main Authors: Spinner, Christoph D, Wille, Florian, Schwerdtfeger, Christiane, Thies, Philipp, Tanase, Ursula, Von Figura, Guido, Schmid, Roland M, Heinz, Werner J, Klinker, Hartwig Hf
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
Subjects:
Short Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297374/
https://ncbi.nlm.nih.gov/pubmed/25598834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12981-014-0041-8
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