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Inducible costimulatory molecule deficiency induced imbalance of Treg and Th17/Th2 delays rejection reaction in mice undergoing allogeneic tracheal transplantation

Objective: This study aimed to investigate the role of inducible costimulatory molecule (ICOS) pathway in the rejection reaction of mice undergoing allogeneic tracheal transplantation. Methods: The bronchus was separated from wide-type (WT) BalB/c mice and transplanted into WT BalB/c mice, C57 mice...

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Bibliographische Detailangaben
Veröffentlicht in:Am J Transl Res
Hauptverfasser: Xu, Jingsong, Wu, Yu, Wang, Guifang, Qin, Yanghua, Zhu, Li, Tang, Gusheng, Shen, Qian
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297345/
https://ncbi.nlm.nih.gov/pubmed/25628788
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