Activation of Keap1/Nrf2 signaling pathway by nuclear epidermal growth factor receptor in cancer cells

Nuclear translocation of EGFR has been shown to be important for tumor cell growth, survival, and therapeutic resistance. Previously, we detected the association of EGFR with Keap1 in the nucleus. Keap1 is a Kelch-like ECH-associated protein, which plays an important role in cellular response to che...

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Dades bibliogràfiques
Publicat a:Am J Transl Res
Autors principals: Huo, Longfei, Li, Chia-Wei, Huang, Tzu-Hsuan, Lam, Yung Carmen, Xia, Weiya, Tu, Chun, Chang, Wei-Chao, Hsu, Jennifer L, Lee, Dung-Fang, Nie, Lei, Yamaguchi, Hirohito, Wang, Yan, Lang, Jingyu, Li, Long-Yuan, Chen, Chung-Hsuan, Mishra, Lopa, Hung, Mien-Chie
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2014
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297334/
https://ncbi.nlm.nih.gov/pubmed/25628777
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