Activation of Keap1/Nrf2 signaling pathway by nuclear epidermal growth factor receptor in cancer cells

Nuclear translocation of EGFR has been shown to be important for tumor cell growth, survival, and therapeutic resistance. Previously, we detected the association of EGFR with Keap1 in the nucleus. Keap1 is a Kelch-like ECH-associated protein, which plays an important role in cellular response to che...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Huo, Longfei, Li, Chia-Wei, Huang, Tzu-Hsuan, Lam, Yung Carmen, Xia, Weiya, Tu, Chun, Chang, Wei-Chao, Hsu, Jennifer L, Lee, Dung-Fang, Nie, Lei, Yamaguchi, Hirohito, Wang, Yan, Lang, Jingyu, Li, Long-Yuan, Chen, Chung-Hsuan, Mishra, Lopa, Hung, Mien-Chie
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297334/
https://ncbi.nlm.nih.gov/pubmed/25628777
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